My research career has focused on the physiology and pathophysiology of the microcirculation, and in recent years, much of our work has been an investigation of the retinal microvascular complications of diabetes and hypertension. Our lab is currently funded with an NIH R01 entitled “Retinal vasculature in hypertension”, and we also have ongoing projects related to other retinal pathologies.
Techniques that we use in the laboratory include intravital microscopy, measurement of microvascular flow, computerized video analysis of microscope images, immunostaining of tissue sections, culturing of retinal microvascular endothelial cells, and various molecular biology techniques and assays.
Below is one of our images of the retinal vasculature (in green) and neuronal nuclei (in red).
Kaur G, Leskova W and Harris NR. The endothelial glycocalyx and retinal hemodynamics. Pathophysiology 29: 663-677, 2022.
Kaur G, Song Y, Xia K, McCarthy K, Zhang F, Linhardt RJ and Harris NR. Effect of high glucose on glycosaminoglycans in cultured retinal endothelial cells and rat retina. Glycobiology. 2022 May 12:cwac029.
Kaur G, Rogers J, Rashdan NA, Cruz-Topete D, Pattillo CB, Hartson SD and Harris NR. Hyperglycemia-induced effects on glycocalyx components in the retina. Experimental Eye Research. Dec; 213:108846, 2021.
Eshaq RS and Harris NR. The role of tumor necrosis factor- and interferon- in the hyperglycemia-induced ubiquitination and loss of platelet endothelial cell adhesion molecule-1 in rat retinal endothelial cells. Microcirculation. Oct; e12717, 2021.
Lee M, Leskova W, Eshaq RS and Harris NR. Retinal hypoxia and angiogenesis with methamphetamine. Experimental Eye Research. May; 206:108540, 2021.
Complete List of my Published Work in MyBibliography: LEARN MORE
Congratulations to Dr. Norman Harris, Chair, Department of Molecular and Cellular Physiology. Dr. Harris recently received a Notice of Award for an RO1 grant. The award is for "Retinal Vasculature in Hypertension", and is for $1,460,000 over four years. The grant begins on Sept. 30, 2022.
Congratulations to Dr. Gaganpreet Kaur, PhD, who completed her PhD degree in May 2022 in the Harris Lab.
She was awarded the highest honor of the Graduate School class of 2022, the Chancellor’s Award.
In addition, she won the following awards over the past two years:
Outstanding ePoster Awards at Vascular Biology 2020 and Vascular Biology 2021
An award from Regeneron at the 2021 Association for Ocular Pharmacology and Therapeutics conference.
The Graduate Poster Presentation Winner at the 2021 LSUS Regional Student Scholar Forum
The Excellence in Health Literacy Award and Judge’s Favorite Presentation at LSUHSC-Shreveport IDEAS DAYS 2021
Zweifach Student Travel Award from the Microcirculatory Society at Experimental Biology 2022
The inaugural D. Neil Granger Graduate Student Award at the Feist Cardiovascular Research Symposium 2022
While we are not currently recruiting Post-doctoral Fellows, quality candidates will always be considered. To enquire about opportunities, contact Dr. Harris at norman.harris@lsuhs.edu.
Graduate Students
Graduate students interested in conducting research in the Harris lab should review the current laboratory research directions and contact Dr. Harris at norman.harris@lsuhs.edu.
Undergraduate Research Assistants
We are not currently hiring any additional undergraduates. However, positions can become available during the summer.
Medical Students, Residents, and Fellows
The Harris laboratory has a number of research projects available for any Medical Students, Residents, and Fellows. Those interested should contact Dr. Harris at norman.harris@lsuhs.edu for more information.
